Concentration Details

Metabolite
HMDB0003634 (Perillyl alcohol)
Biospecimen
Blood
Status
Detected and Quantified
Data source
Referenced
Concentration
0.028 (0.023 - 0.032) uM
Age
Adult (>18 years old)
Sex
Female
Condition
Perillyl alcohol administration for cancer treatment
Comments
AJCC Stage I–IIIa breast cancer after oral administration of 500mg/m2 of perillyl alcohol. Ref: The clinical study is a part of an ongoing Phase I evaluation of POH as a chemopreventative agent at the Cleveland Clinic Foundation. POH was measured in a patient (plasma) following p.o. administration of POH at 500 mg/m2.
References
    1. Zhang Z, Chen H, Chan KK, Budd T, Ganapathi R: Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma. J Chromatogr B Biomed Sci Appl. 1999 May 14;728(1):85-95. [PubMed:10379660 ]